Facile Stereoselective Synthesis of the C12-C24 Fragment of Macrolactin-A

Jhillu S. Yadav; Manoj K. Gupta; I. Prathap

doi:10.1055/s-2007-966010

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Facile Stereoselective Synthesis of the C12-C24 Fragment of Macrolactin-A

Jhillu S. Yadav*, Manoj K. Gupta, I. Prathap
Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Fax: +91(40)27160512; e-Mail: yadavpub@iict.res.in;

Abstract

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Abstract

A simple and efficient stereoselective synthesis of the C12-C24 fragment of the natural product macrolactin-A was achieved from d-glucose as the starting material and with use of the Wittig and modified Julia olefination reactions as key steps.

Key words

d-glucose - Raney nickel - Wittig reaction - modified Julia olefination

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References

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